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Hydraphile Cation Channels

Hydraphile channels use crown ethers as amphiphilic head groups and as entry portals to create a pore within a bilayer membrane. Cations transport through the channels, which exhibit classic open-close behavior typical of protein channels.

Amphiphilic Peptides

A family of synthetic anion transporters (SATs) has been prepared. These extensively substituted peptide derivatives mediate the transport of chloride and other anions through phospholipid bilayers.

Cation-pi Interaction

Synthetic receptors have been used to define the interactions between alkali metal cations and benzene, phenol, and indole, the common amino acid arenes.




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